This course introduces you to the basic biology of modern genomics and the experimental tools that we use to measure it. We'll introduce the Central Dogma of Molecular Biology and cover how next-generation sequencing can be used to measure DNA, RNA, and epigenetic patterns. You'll also get an introduction to the key concepts in computing and data science that you'll need to understand how data from next-generation sequencing experiments are generated and analyzed.
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課程信息
您將獲得的技能
- Bioinformatics
- Statistics
- Data Science
- Computational Biology
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约翰霍普金斯大学
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
授課大綱 - 您將從這門課程中學到什麼
Overview
In this Module, you can expect to study topics of "Just enough molecular biology", "The genome", "Writing a DNA sequence", "Central dogma", "Transcription", "Translation", and "DNA structure and modifications".
Measurement Technology
In this module, you'll learn about polymerase chain reaction, next generation sequencing, and applications of sequencing.
Computing Technology
The lectures for this module cover a few basic topics in computing technology. We'll go over the foundations of computer science, algorithms, memory and data structures, efficiency, software engineering, and computational biology software.
Data Science Technology
In this module on Data Science Technology, we'll be covering quite a lot of information about how to handle the data produced during the sequencing process. We'll cover reproducibility, analysis, statistics, question types, the central dogma of inference, analysis code, testing, prediction, variation, experimental design, confounding, power, sample size, correlation, causation, and degrees of freedom.
審閱
- 5 stars66.16%
- 4 stars27.12%
- 3 stars5.25%
- 2 stars0.91%
- 1 star0.53%
來自基因组技术基础的熱門評論
Complex topics summarized to key points, which is great. One criticism is that some questions on the quizzes required prior knowledge (fact recall) that wasn't covered in the course
This course had gave me the overview of the statistical analyses for genomic data analysis. This is useful for me as I can employ those statistical Analyses knowledge in the near future
Thanks to everyone who made this. Such can wait to start the second course. h a superb course; it started slowly and sort of an easy thing, but the last lecture was phenomenal
The final project was way more work than any of the other weeks (10 hours!), but it was definitely worth stumbling my way around Galaxy and foreign genomic terms for that long.
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