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學生對 西奈山伊坎医学院 提供的 系统生物学导论 的評價和反饋

4.3
438 個評分
94 條評論

課程概述

This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems? The course will develop multiple lines of reasoning to answer the questions listed above. Two major reasoning threads are: the design, execution and interpretation of multivariable experiments that produce large data sets; quantitative reasoning, models and simulations. Examples will be discussed to demonstrate “how” cell- level functions arise and “why” mechanistic knowledge allows us to predict cellular behaviors leading to disease states and drug responses....

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SV
2016年2月6日

Very useful course in order to learn the basics in systems biology. You only need some training in biology to understand the concepts but the course is easy to follow and very complete.

BR
2019年8月7日

Great foundational material and insights from Prof. Iyengar that supports the 'disruptive' trends underway at the intersection of Computational Biology and Medicine.

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76 - 系统生物学导论 的 92 個評論(共 92 個)

創建者 Karl D

2017年7月26日

Good overview of systems biology, but the graded tests are somewhat difficult to understand for someone without a biology background such as myself.

創建者 Connie N

2020年10月1日

Really interesting content, but could use a rework on formatting, style, and clarity.

創建者 Alan R d F K M

2020年1月20日

Could give more basic information about systems theory

創建者 Milena J

2016年2月12日

The lectures were somehow chaotic.

創建者 Mainak B

2020年2月23日

Tough and brain storming

創建者 Soheyl M

2020年11月27日

The explanations in the course are extremely superficial and do not add anything to the PowerPoint presented in each course. In addition, most of the articles presented in the lectures are hardly discussed which makes it difficult to understand for a beginner in this field.

創建者 Circe M

2017年8月11日

Course material was not presented in a matter that flowed naturally. Completing the course didn't lend greatly to my overall understanding in the area though I understand certain aspects very well.

創建者 Carolina A

2020年4月19日

I found that the lectures didn't guide me enough. I download the articles and read extra material. I will look for another course to learn more of this part of the specialization.

創建者 Alexandro G A S

2016年8月9日

It is a good introductory course, but it relies too much on networks and could be confusing and demoralizing if you intend to pursue a career in systems biology.

創建者 D C

2019年11月6日

The course is too specific and advanced. It´s not an introduction.

創建者 Sergey K

2015年12月19日

Boring voice. A lot of overcomplicated terms, where you can describe your idea in a much more simple way. In result i feel that lector read this material not to teach people, but just to read it. Disgusting.

創建者 Donna P

2016年3月12日

I could not understand instructor. Using subtitles didn't help either as many words came up unintelligible.

創建者 Alexander

2016年10月5日

The material is very randomized, and the instructor presents it in an overly complex way.

創建者 Richelle E

2020年10月18日

the course/ lecture session doesnt highlight half the stuff that pops up in the exams

創建者 Ahmed N

2020年5月6日

i want to cancel mt subscription in this course

創建者 Ezequiel O G

2020年7月2日

muy malo, no lo recomiendo, para nada

創建者 YKALYAN K

2020年6月6日

too boring