This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems?
The Icahn School of Medicine at Mount Sinai, in New York City is a leader in medical and scientific training and education, biomedical research and patient care.
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Very useful course in order to learn the basics in systems biology. You only need some training in biology to understand the concepts but the course is easy to follow and very complete.
Great foundational material and insights from Prof. Iyengar that supports the 'disruptive' trends underway at the intersection of Computational Biology and Medicine.
It's a challenging subject. Don't expect to walk away from the course with a complete grasp of systems biology. However, this course is a fantastic place to start.
Great course! The only change i would ask for: after the test, could you let us see the correct response to the questions we got wrong? Thanks!
Nice course, a little boring at the beginning with so much data about cell signaling, (kinases names, and specific routes).
Ravi is a great researcher. This class is taught with great clarity and expertise. Subtitle is much less impressive though.
Excellent course, could be improved by explaining the more difficult concepts in greater depth, e.g. ODE and PDE math.
Very nice course, would have liked more interactivity / problem solving type questions
Great introduction and overview. Exams are especially well thought out.
Really great course! Can't wait to learn more about systems biology!
that corse was really beneficial and useful for me. Thanks a lot
fascinating, difficult, and interesting course. Thanks so much!
關於 系统生物学与生物技术 專項課程