In this course, you will learn how to use the BaseSpace cloud platform developed by Illumina (our industry partner) to apply several standard bioinformatics software approaches to real biological data.
提供方
生物信息学 專項課程加州大学圣地亚哥分校課程信息
3,615 次近期查看
學生職業成果
33%
完成這些課程後已開始新的職業生涯
33%
通過此課程獲得實實在在的工作福利
可分享的證書
完成後獲得證書
100% 在線
立即開始，按照自己的計劃學習。
第 7 門課程（共 7 門）
可靈活調整截止日期
根據您的日程表重置截止日期。
初級
完成時間大約為14 小時
英語（English）
字幕：英語（English）
學生職業成果
33%
完成這些課程後已開始新的職業生涯
33%
通過此課程獲得實實在在的工作福利
可分享的證書
完成後獲得證書
100% 在線
立即開始，按照自己的計劃學習。
第 7 門課程（共 7 門）
可靈活調整截止日期
根據您的日程表重置截止日期。
初級
完成時間大約為14 小時
英語（English）
字幕：英語（English）
提供方
加州大学圣地亚哥分校
UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 10 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom—life is their laboratory.
教學大綱 - 您將從這門課程中學到什麼
完成時間為 5 小時
Week 1: Identifying the Culprit in a Food Poisoning Outbreak
This week, we will apply genome sequencing algorithms to identify the bacterium causing a deadly food poisoning outbreak.
完成時間為 5 小時
5 個閱讀材料
5 個閱讀材料
Note on Course Structure10分鐘
Welcome to Class!10分鐘
Special Thanks2分鐘
Introduction15分鐘
Databases and Tools5分鐘
完成時間為 4 小時
Week 2: Comparing Gene Expression in Tissue Samples with RNA-Seq
In this week's Application Challenge, we will learn how RNA-Sequencing can be applied to perform tissue-level gene expression analysis. In particular, which is more similar on a gene expression level: different tissues from the same organism, or analogous tissues from related species? This question was the subject of recent debate and a Twitter controversy -- read more to find out!
完成時間為 4 小時
2 個閱讀材料
2 個閱讀材料
Introduction15分鐘
Databases and Tools5分鐘
完成時間為 5 小時
Week 3: Weighing the Pros and Cons of Whole Genome and Whole Exome Sequencing on a Human Sample
Comparing the differences between sequencing an entire human genome and sequencing only the exome, or the DNA that is eventually translated into protein. Can we obtain a complete picture of someone's genetic disease predispositions from only the exome, or is there information lurking in introns that can provide doctors with vital information? How do we weigh the trade-offs when considering genome and exome sequencing?
完成時間為 5 小時
4 個閱讀材料
4 個閱讀材料
Introduction15分鐘
Databases and Tools10分鐘
Walkthroughs15分鐘
Reading: Part 3 FAQs
關於 生物信息学 專項課程
Join Us in a Top 50 MOOC of All Time!
How do we sequence and compare genomes? How do we identify the genetic basis for disease? How do we construct an evolutionary Tree of Life for all species on Earth?
When you complete this Specialization, you will learn how to answer many questions in modern biology that have become inseparable from the computational approaches used to solve them. You will also obtain a toolkit of existing software resources built on these computational approaches and that are used by thousands of biologists every day in one of the fastest growing fields in science.
Although this Specialization centers on computational topics, you do not need to know how to program in order to complete it. If you are interested in programming, we feature an "Honors Track" (called "hacker track" in previous runs of the course). The Honors Track allows you to implement the bioinformatics algorithms that you will encounter along the way in dozens of automatically graded coding challenges. By completing the Honors Track, you will be a bioinformatics software professional!
Learn more about the Bioinformatics Specialization (including why we are wearing these crazy outfits) by watching our introductory video.
You can purchase the Specialization's print companion, Bioinformatics Algorithms: An Active Learning Approach, from the textbook website.
Our first course, "Finding Hidden Messages in DNA", was named a top-50 MOOC of all time by Class Central!
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