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完成時間大約為95 小時
英語(English)
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可分享的證書
完成後獲得證書
100% 在線
立即開始,按照自己的計劃學習。
可靈活調整截止日期
根據您的日程表重置截止日期。
中級
完成時間大約為95 小時
英語(English)
字幕:英語(English)

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约翰霍普金斯大学 徽標

约翰霍普金斯大学

教學大綱 - 您將從這門課程中學到什麼

1

1

完成時間為 75 小時

Module 1

完成時間為 75 小時
10 個視頻 (總計 121 分鐘), 3 個閱讀材料, 1 個測驗
10 個視頻
Course Introduction16分鐘
Introduction49
Center for Alternatives to Animal Testing4分鐘
Toxicology of the Fifteenth to Twentieth Centuries15分鐘
Toxicology for the Twenty-First Century15分鐘
Historical Perspective17分鐘
The First Report: Toxicity Testing for Assessment of Environmental Agents11分鐘
The Second Report: Toxicity Testing in the 21st Century: A Vision and A Strategy Vision and Its Components22分鐘
The Second Report: Toxicity Testing in the 21st Century: A vision and A Strategy Implementation13分鐘
3 個閱讀材料
useful links20分鐘
supporting reading material10分鐘
Supporting reading material10分鐘
1 個練習
Module 1 Quiz
2

2

完成時間為 5 小時

Module 2

完成時間為 5 小時
10 個視頻 (總計 119 分鐘), 4 個閱讀材料, 2 個測驗
10 個視頻
Adverse Outcome Pathways (AOPs)10分鐘
Exposure-Based Chemical Prioritization13分鐘
ER Bioactivity Model16分鐘
US EPA Endocrine Disruptor Screening Program (EDSP)17分鐘
Modeling of Hazard and Organ Manifestation11分鐘
Building a Signature for Vascular Disruption10分鐘
Testing the Vascular Disruption Signature8分鐘
Virtual Tissue Model: Vascular Development12分鐘
Functional Vascular Development Assays16分鐘
4 個閱讀材料
Supporting Reading Material10分鐘
Useful links10分鐘
Supporting Reading Material10分鐘
Useful links10分鐘
1 個練習
Module 2 Quiz8分鐘
3

3

完成時間為 3 小時

Module 3

完成時間為 3 小時
11 個視頻 (總計 126 分鐘), 2 個閱讀材料, 1 個測驗
11 個視頻
Mechanistic Toxicology and Pathway Mapping at the Basics of 21st Century Toxicology16分鐘
The Concept of the Human Toxome Project21分鐘
Concept and Tool Devlopment11分鐘
Progress7分鐘
Conclusions and Prospectives8分鐘
Introduction - What Is a Pathway of Toxicity, and Why Do We Need Them?6分鐘
Omics Technologies and High-Throughput Data11分鐘
Interpreting Omics Data11分鐘
PoT Examples and Conclusions15分鐘
Pathways of Toxicity and Adverse Outcome Pathways (AOPs)13分鐘
2 個閱讀材料
Supporting reading materials10分鐘
Supporting reading material10分鐘
1 個練習
Module 3 Quiz8分鐘
4

4

完成時間為 4 小時

Module 4

完成時間為 4 小時
15 個視頻 (總計 148 分鐘), 3 個閱讀材料, 2 個測驗
15 個視頻
The Concept of Toxicological (Biological) Pathways, e.g., “Adverse Outcome Pathways,” Is the Basis of Predictive Toxicology5分鐘
Introduction to the OECD AOP Framework10分鐘
Building, Evaluating, and Using AOPs in Safety Decisions6分鐘
Online Tools Available to Everyone, Including an Online AOP Course4分鐘
Welcome to Module 42分鐘
Introduction to Read-Across18分鐘
Good Read-Across Practice21分鐘
Supporting Read-Across with Biological Data12分鐘
Creating a Database of Toxicity12分鐘
Creating an Automated Tool for Read-Across9分鐘
Paradigm Shift in Toxicology7分鐘
2D In Vitro Cell Culture8分鐘
3D In Vitro Cell Cultures8分鐘
Organ-on-a-Chip11分鐘
3 個閱讀材料
Supporting reading material10分鐘
Supporting reading material10分鐘
Useful links10分鐘
2 個練習
Module 4 Quiz8分鐘
Mid-term exam44分鐘
完成時間為 1 小時

Module 5

完成時間為 1 小時
6 個視頻 (總計 41 分鐘), 1 個閱讀材料, 1 個測驗
6 個視頻
MicroRNA and Epigenetics4分鐘
Epigenetics and Environment6分鐘
MicroRNA: Biogenesis and Functions11分鐘
Role of MicroRNA in Development6分鐘
MicroRNA in Toxicology9分鐘
1 個閱讀材料
Supporting reading material10分鐘
1 個練習
Module 5 Quiz8分鐘

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