This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems?
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課程信息
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西奈山伊坎医学院
The Icahn School of Medicine at Mount Sinai, in New York City is a leader in medical and scientific training and education, biomedical research and patient care.
授課大綱 - 您將從這門課程中學到什麼
Systems Level Reasoning | Molecules to Pathways
Module description goes here.
Pathways to Networks | Physical Forces and Electrical Activity in Cell Biology
Module description goes here.
Mathematical Representations of Cell Biological Systems | Simulations of Cell Biological Systems
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Experimental Technologies | Network Building and Analysis
Module description goes here.
審閱
- 5 stars56.97%
- 4 stars25.23%
- 3 stars8.79%
- 2 stars5.16%
- 1 star3.82%
來自系统生物学导论的熱門評論
that corse was really beneficial and useful for me. Thanks a lot
I enjoyed the topics that were covered in the course. I removed one star because the quizes required deeper knowledge than what was covered during the lectures.
Coursera make it different... I'm pretty lucky to find a systems biology course like this.
Ravi is a great researcher. This class is taught with great clarity and expertise. Subtitle is much less impressive though.
關於 系统生物学与生物技术 專項課程
Design systems-level experiments using appropriate cutting edge techniques, collect big data, and analyze and interpret small and big data sets quantitatively.

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