關於此課程：我们将介绍对临床试验进行系统综述和元分析的方法，课程内容包括如何构建一个能够回答的研究问题，确定收入和排除条件，寻找证据，提取数据，评价临床试验中偏倚的风险，并进行元分析。 顺利完成课程后，同学们将能够： -描述进行系统综述的步骤 -采用“受试者，干预措施，比较方法，结果”(PICO)框架来提出能够回答的问题 -描述从临床试验报告中收集和提取数据的过程 -描述辩证地分析临床试验偏倚风险的方法 -描述和解释元分析的结果
製作方： Johns Hopkins University
教學方： Tianjing Li, MD, MHS, PHD, Assistant Professor, Epidemiology
Bloomberg School of Public Health教學方： Kay Dickersin, PhD, Professor, Epidemiology
Bloomberg School of Public Health
| 承諾學習時間 | 6周的学习;4-6小时/每周 |
| 語言 | English |
| 如何通過 | 通過所有計分作業以完成課程。 |
| 用戶評分 |
授課大綱
第 1 週
Introduction
To get the ball rolling, we'll take a broad overview of what to expect in this course and then introduce you to the high-level concepts of systematic review and meta-analysis and take a look at who produces and uses systematic reviews.
5 個視頻, 3 個閱讀材料
- Reading: Syllabus
- Reading: Pre Course Survey
- Reading: From the Field Videos
- 視頻: Lecture 1A : Introduction to Systematic Reviews
- 視頻: Lecture 1B: Introduction to Meta-Analysis
- 視頻: Lecture 1C: Producers and Users of Systematic Reviews
- 視頻: Hannah Rothstein, PhD
第 2 週
Framing the Question
In this module, we will discuss how to frame a question, as well as scope, elements, and refining the question.
7 個視頻, 1 個閱讀材料
- 視頻: Lecture 2B: Deciding the Type and Scope of Your Question
- 視頻: Lecture 2C: Elements of the Question
- 視頻: Lecture 2D: Refining the Question
- 視頻: Lecture 2E: Some Examples
- 視頻: Lecture 2F: Analytic Frameworks
- 視頻: Betsy Becker, PhD
- Reading: Welcome to the first Peer Assignment!
已評分: Module 2
已評分: Peer Assessment 1
第 3 週
Searching Principles and Bias Assessment
In this module we will look at finding the evidence, as well as key sources, search strategy, and assessing the risk of bias.
11 個視頻
- 視頻: Lecture 3A: Finding the Evidence: Searching Principles
- 視頻: Lecture 3B: Identifying Key Sources and Techniques for Searching
- 視頻: Lecture 3C: Building a High-Quality Search Strategy
- 視頻: Lecture 3D: Documenting Your Search and Conclusions
- 視頻: Lecture 4A: Why Bias in the Individual Study is Important to a Systematic Review and Meta-Analysis
- 視頻: Lecture 4B: Selection Bias
- 視頻: Lecture 4C: Information Bias
- 視頻: Lecture 4D: Bias in the Analysis
- 視頻: Lecture 4E: Displaying Study "Quality" in Your Systematic Review
- 視頻: Byron Wallace, Phd
已評分: Module 3
已評分: Module 4
第 4 週
Minimizing Metabias, Qualitative Synthesis, and Interpreting Results
In this module, we will cover minimizing metabias, selection bias, information bias, how to report transparently, qualitative synthesis, and interpreting results.
9 個視頻
- 視頻: Lecture 5B: Selection Bias
- 視頻: Lecture 5C: Information Bias
- 視頻: Lecture 5D: Bias in the Analysis
- 視頻: Lecture 5E: Reporting Transparently
- 視頻: Lecture 6A: Qualitative Synthesis and Interpreting Results Section A
- 視頻: Lecture 6B: What is Qualitative Synthesis
- 視頻: Lecture 6C: Some Examples
- 視頻: Christopher Schmid, PhD
已評分: Module 5
已評分: Module 6
第 5 週
Planning the Meta-Analysis and Statistical Methods
This module will cover the planning of your meat-analysis and the statistical methods for meta-analysis.
9 個視頻
- 視頻: Lecture 7A: Planning Your Meta-Analysis Section A
- 視頻: Lecture 7B: Introduction to Meta-Analysis
- 視頻: Lecture 7C: Why Do a Meta-Analysis?
- 視頻: Lecture 7D: Types of Data and Effect Measures
- 視頻: Lecture 8A: Fixed Effect Model
- 視頻: Lecture 8B: Random Effects Model
- 視頻: Lecture 8C: Random Effects Model
- 視頻: Michael Borenstein, PhD
已評分: Module 7
已評分: Module 8
第 6 週
Wrap Up and Final Peer Review Assignment
In this final module, we'll wrap up with a look back at the key concepts covered over the past few weeks. Afterwards, you will submit your final Peer Review Assignment and evaluate some of your classmates' submissions.
2 個視頻, 1 個閱讀材料
- Reading: Welcome to Your Final Peer Review Assignment
- 視頻: Closing Remarks
已評分: Peer Review Assignment 2
常見問題解答
運作方式
Coursework
Each course is like an interactive textbook, featuring pre-recorded videos, quizzes and projects.
Help from Your Peers
Connect with thousands of other learners and debate ideas, discuss course material, and get help mastering concepts.
Certificates
Earn official recognition for your work, and share your success with friends, colleagues, and employers.
製作方
Johns Hopkins University
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
評分和審閱
I loved everything about this course! I learned a lot and I am proud to say that now I can critically read a systematic review and interpret meta-analysis results. I will definitely do another Johns Hopkins course in the future!
I would have liked to have learned more about generating forest plots, additional data visualizations of meta-analysis, and additional examples of meta-analysis....
The course talked about the PRISMA methods in achieving systematic reviews, is PRISMA a standard method in systematic reviews (e.g. universality) in structuring or are different entities then Cochrane achieving systematic reviews in different, yet, comparable PRISMA methods?
It is a excellent option to learn about sitematic review and meta analysis, basics concepts with the posibility to go deeper as you can do.
Ie
Brilliant course .