We will introduce methods to perform systematic reviews and meta-analysis of clinical trials. We will cover how to formulate an answerable research question, define inclusion and exclusion criteria, search for the evidence, extract data, assess the risk of bias in clinical trials, and perform a meta-analysis.
Upon successfully completing this course, participants will be able to:
- Describe the steps in conducting a systematic review
- Develop an answerable question using the “Participants Interventions Comparisons Outcomes” (PICO) framework
- Describe the process used to collect and extract data from reports of clinical trials
- Describe methods to critically assess the risk of bias of clinical trials
- Describe and interpret the results of meta-analyses
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约翰霍普金斯大学
教學大綱 - 您將從這門課程中學到什麼
週
1完成時間為 1 小時
Introduction
To get the ball rolling, we'll take a broad overview of what to expect in this course and then introduce you to the high-level concepts of systematic review and meta-analysis and take a look at who produces and uses systematic reviews.
5 個視頻 （總計 40 分鐘）, 3 個閱讀材料
5 個視頻
Lecture 1A : Introduction to Systematic Reviews15分鐘
Lecture 1B: Introduction to Meta-Analysis12分鐘
Lecture 1C: Producers and Users of Systematic Reviews8分鐘
Hannah Rothstein, PhD1分鐘
3 個閱讀材料
Syllabus10分鐘
Pre Course Survey10分鐘
From the Field Videos10分鐘
週
2完成時間為 4 小時
Framing the Question
In this module, we will discuss how to frame a question, as well as scope, elements, and refining the question.
7 個視頻 （總計 73 分鐘）, 1 個閱讀材料, 2 個測驗
7 個視頻
Lecture 2B: Deciding the Type and Scope of Your Question17分鐘
Lecture 2C: Elements of the Question16分鐘
Lecture 2D: Refining the Question10分鐘
Lecture 2E: Some Examples8分鐘
Lecture 2F: Analytic Frameworks10分鐘
Betsy Becker, PhD2分鐘
1 個閱讀材料
Welcome to the first Peer Assignment!10分鐘
1 個練習
Module 210分鐘
週
3完成時間為 2 小時
Searching Principles and Bias Assessment
In this module we will look at finding the evidence, as well as key sources, search strategy, and assessing the risk of bias.
11 個視頻 （總計 119 分鐘）, 2 個測驗
11 個視頻
Lecture 3A: Finding the Evidence: Searching Principles5分鐘
Lecture 3B: Identifying Key Sources and Techniques for Searching17分鐘
Lecture 3C: Building a High-Quality Search Strategy17分鐘
Lecture 3D: Documenting Your Search and Conclusions8分鐘
Lecture 4A: Why Bias in the Individual Study is Important to a Systematic Review and Meta-Analysis7分鐘
Lecture 4B: Selection Bias18分鐘
Lecture 4C: Information Bias8分鐘
Lecture 4D: Bias in the Analysis15分鐘
Lecture 4E: Displaying Study "Quality" in Your Systematic Review16分鐘
Byron Wallace, Phd2分鐘
2 個練習
Module 310分鐘
Module 410分鐘
週
4完成時間為 2 小時
Minimizing Metabias, Qualitative Synthesis, and Interpreting Results
In this module, we will cover minimizing metabias, selection bias, information bias, how to report transparently, qualitative synthesis, and interpreting results.
9 個視頻 （總計 88 分鐘）, 2 個測驗
9 個視頻
Lecture 5B: Selection Bias22分鐘
Lecture 5C: Information Bias12分鐘
Lecture 5D: Bias in the Analysis15分鐘
Lecture 5E: Reporting Transparently6分鐘
Lecture 6A: Qualitative Synthesis and Interpreting Results Section A7分鐘
Lecture 6B: What is Qualitative Synthesis10分鐘
Lecture 6C: Some Examples5分鐘
Christopher Schmid, PhD1分鐘
2 個練習
Module 510分鐘
Module 610分鐘
週
5完成時間為 2 小時
Planning the Meta-Analysis and Statistical Methods
This module will cover the planning of your meat-analysis and the statistical methods for meta-analysis.
9 個視頻 （總計 109 分鐘）, 2 個測驗
9 個視頻
Lecture 7A: Planning Your Meta-Analysis Section A7分鐘
Lecture 7B: Introduction to Meta-Analysis15分鐘
Lecture 7C: Why Do a Meta-Analysis?10分鐘
Lecture 7D: Types of Data and Effect Measures19分鐘
Lecture 8A: Fixed Effect Model20分鐘
Lecture 8B: Random Effects Model14分鐘
Lecture 8C: Random Effects Model17分鐘
Michael Borenstein, PhD2分鐘
2 個練習
Module 710分鐘
Module 810分鐘
週
6完成時間為 2 小時
Wrap Up and Final Peer Review Assignment
In this final module, we'll wrap up with a look back at the key concepts covered over the past few weeks. Afterwards, you will submit your final Peer Review Assignment and evaluate some of your classmates' submissions.
2 個視頻 （總計 13 分鐘）, 1 個閱讀材料, 1 個測驗
1 個閱讀材料
Welcome to Your Final Peer Review Assignment10分鐘
4.7
279 個審閱30%
完成這些課程後已開始新的職業生涯
21%
通過此課程獲得實實在在的工作福利
10%
加薪或升職
熱門審閱
Although introductory, I do carry out reviews as a researcher. I Learned a lot to improve my systematic reviews through this course. High quality, though the music could be a little less intense.
Incredible course! You learned a lot from these amazing professors. If you take this course you will know how to do a high quality systematic review and even a meta analysis and publish them.
講師
Tianjing Li, MD, MHS, PHD
Assistant Professor, EpidemiologyBloomberg School of Public Health
Kay Dickersin, PhD
Professor, EpidemiologyBloomberg School of Public Health
關於 约翰霍普金斯大学
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
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