課程信息
4.7
12 ratings
6 reviews
Synbio is a diverse field with diverse applications, and the different contexts (e.g., gain-of-function research, biofuels) raise different ethical and governance challenges. The objective of this course is to increase learners’ awareness and understanding of ethical and policy/governance issues that arise in the design, conduct and application of synthetic biology. The course will begin with a short history of recombinant DNA technology and how governance of that science developed and evolved, and progress through a series of areas of application of synbio. Content will be presented in many forms, including not only reading and lectures, but also recorded and live interviews and discussions with scientists, ethicists and policy makers. Learners will have the opportunity to think, write and talk about the issues and challenges in their own work and in real-life case examples. A final project will engage students in the development of governance models for synbio....
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Intermediate Level

中級

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建議:6 weeks of study, 2-4 hours/week

完成時間大約為17 小時
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English

字幕:English
Globe

100% 在線課程

立即開始,按照自己的計劃學習。
Calendar

可靈活調整截止日期

根據您的日程表重置截止日期。
Intermediate Level

中級

Clock

建議:6 weeks of study, 2-4 hours/week

完成時間大約為17 小時
Comment Dots

English

字幕:English

教學大綱 - 您將從這門課程中學到什麼

1

章節
Clock
完成時間為 18 分鐘

Welcome to Engineering Life: SynBio, Bioethics & Public Policy

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Reading
1 個視頻(共 3 分鐘), 1 個閱讀材料
Video1 個視頻
Reading1 個閱讀材料
Syllabus: Engineering Life10分鐘
Clock
完成時間為 2 小時

Recombinant DNA Technology: Science and History

We start the course by learning a bit about the history and context of the development of recombinant DNA (rDNA) technology in the 1970s, the ethics and policy issues raised by that science, and how those issues remain with us today in synthetic biology. The work of the week includes lecture videos, readings, and an interview with LeRoy Walters, who was involved in the discussions and debates about rDNA in its early years. The week will conclude with a quiz....
Reading
8 個視頻(共 105 分鐘), 1 個閱讀材料, 1 個測驗
Video8 個視頻
A Brief History of rDNA15分鐘
A Brief History of Asilomar & the RAC19分鐘
Interview: Dr. LeRoy Walters (Part 1)19分鐘
Interview: Dr. LeRoy Walters (Part 2)21分鐘
Interview: Dr. LeRoy Walters (Part 3)12分鐘
Relevant Contemporary Policy Context5分鐘
The Emergence of SynBio9分鐘
Reading1 個閱讀材料
Week 1 Readings10分鐘
Quiz1 個練習
Week 1 Quiz30分鐘

2

章節
Clock
完成時間為 3 小時

GOF Research

In Week 2 we will learn about and discuss gain of function (GOF) research and the dual-use concerns raised by synthetic biology. The work of the week includes lecture videos, a number of outside videos, and readings. The assessment this week will be your first peer-assessed project, and will focus on identifying ethical duties related to GOF research policy....
Reading
6 個視頻(共 49 分鐘), 2 個閱讀材料, 1 個測驗
Video6 個視頻
Gain of Function Research5分鐘
Dual Use Research9分鐘
GOF Research Case Study: H5N112分鐘
Ethical Issues Raised by GOF Research11分鐘
Governance and GOF Research9分鐘
Reading2 個閱讀材料
Week 2 Readings10分鐘
Additional Video Content10分鐘

3

章節
Clock
完成時間為 2 小時

Biofuels

This week, we’ll learn about biofuels, the complex task of balancing the many ethical issues they raise, and the role of synthetic biology in biofuels development. The work of the week includes lecture videos, one outside video, readings, and an interview with Deborah Scott about biofuels governance. The week will conclude with a quiz....
Reading
7 個視頻(共 69 分鐘), 2 個閱讀材料, 1 個測驗
Video7 個視頻
Biofuels9分鐘
Applications5分鐘
Case Study4分鐘
Ethical Issues Raised by SynBio-based Biofuels8分鐘
Interview: Deborah Scott, PhD, JD (Part 1)24分鐘
Interview: Deborah Scott, PhD, JD (Part 2)14分鐘
Reading2 個閱讀材料
Week 3 Readings10分鐘
Additional Video Content10分鐘
Quiz1 個練習
Week 3 Quiz30分鐘

4

章節
Clock
完成時間為 3 小時

Human Health

This week we will learn a bit about applications of synthetic biology to human health, and the ethics of human subjects research. The work of the week includes lecture videos, one outside video, and readings. The assessment this week will be your second peer-assessed project, and will build on your first project, from Week 2. This project will focus on identifying stakeholders in a policy decision, their interests in the decision, and the related ethical duties of the decision-maker....
Reading
7 個視頻(共 50 分鐘), 2 個閱讀材料, 1 個測驗
Video7 個視頻
Synbio in Human Health5分鐘
Human Genetic Modification6分鐘
Case Study: Artemisinin6分鐘
Case Study: GM Mosquitos8分鐘
Ethical Issues Raised by SynBio-based Medical Applications13分鐘
Governance of SynBio-based Medical Applications7分鐘
Reading2 個閱讀材料
Week 4 Readings10分鐘
Additional Video Content10分鐘
4.7

熱門審閱

創建者 JQJul 28th 2017

fun and interesting course. very well taught by somebody obviously knowledgeable. Thanks so much.

創建者 TNJun 16th 2017

Highly thought-provoking. One of the most interesting classes I have taken on Coursera.

講師

Debra JH Mathews, PhD, MA

Assistant Director for Science Programs
Berman Institute of Bioethics

關於 Johns Hopkins University

The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world....

常見問題

  • Once you enroll for a Certificate, you’ll have access to all videos, quizzes, and programming assignments (if applicable). Peer review assignments can only be submitted and reviewed once your session has begun. If you choose to explore the course without purchasing, you may not be able to access certain assignments.

  • When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.

  • The primary goal of this class is to help scientists think a bit more like policy makers and the public, seeing not only the incredible promise of the science they do, but also the potential risks and pitfalls, so these can be avoided or designed against at the beginning of a project, rather than at the end, when the challenges and costs are higher. Working with scholars, policy makers, and fellow learners, students will gain a greater understanding and appreciation of the ethics and governance of synthetic biology.

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