Translational science seeks to speed up the process of moving research discoveries from the laboratory into healthcare practices. Numerous scientific and organizational roadblocks can act as obstacles along the path of translation and ultimately hinder the speed of progress in medical research. The National Center for Advancing Translational Sciences (NCATS) was established by the National Institutes of Health (NIH) to transform and accelerate the translational research process, with the intended result of getting treatments to more patients faster. The field of Translational Science aims to bridge these gaps by:
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Introduction to Translational Science
罗彻斯特大学
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初級
完成時間大約為8 小時
建議：The six lessons will be covered in three weeks and require approximately 2-3 hours per week.
英語（English）
字幕：英語（English）
提供方
罗彻斯特大学
The University of Rochester is one of the nation's leading private universities. Located in Rochester, N.Y., the University provides exceptional opportunities for interdisciplinary study and close collaboration with faculty through its unique cluster-based curriculum. Its College, School of Arts and Sciences, and Hajim School of Engineering and Applied Sciences are complemented by its Eastman School of Music, Simon School of Business, Warner School of Education, Laboratory for Laser Energetics, School of Medicine and Dentistry, School of Nursing, Eastman Institute for Oral Health, and the Memorial Art Gallery.
教學大綱 - 您將從這門課程中學到什麼
完成時間為 3 小時
Translational Science - The Big Picture and T1 - Translation to Humans
The first lesson in Introduction to Translational Science provides an overview of the basic definitions and key concepts related to clinical and translational science and the CTSA program. Students will learn about the different stages of translational research and the roadblocks that impede progress across the spectrum.The second lesson in Introduction to Translational Science provides an introduction to T1 research which is research that translates findings from basic (laboratory) research to humans through developing treatments and interventions. T1 research is often conducted through observational studies, case studies, proof-of-concept studies, phase I clinical trials, and phase II clinical trials
完成時間為 3 小時
8 個視頻 （總計 59 分鐘）, 5 個閱讀材料, 1 個測驗
8 個視頻
The Big Picture - Part I (7:41)7分鐘
The Big Picture - Part II (9:22)9分鐘
The Big Picture - Part III (5:20)5分鐘
The Big Picture - Part IV (7:00)6分鐘
T1 - Translation to Humans - Introduction (10:48)10分鐘
T1 - Translation to Humans Part I (6:59)6分鐘
T1 - Translation to Humans Part II (8:37)8分鐘
5 個閱讀材料
NCATS Fact Sheet10分鐘
The Clinical and Translational Science Award (CTSA) Consortium and the Translational Research Model15分鐘
Transforming Translation: Impact of Clinical and Translational Science15分鐘
Translational biomarker discovery in clinical metabolomics: an introductory tutorial45分鐘
The hematopoietic stem cell niche in homeostasis and disease15分鐘
1 個練習
Module 1 Quiz40分鐘
完成時間為 3 小時
T2 - Translation to Patients and T3 - Translation to Practice
The third lesson in Introduction to Translational Science provides an introduction to T2 research, which is research that translates findings from T1 research (humans) to patients. T2 research is often conducted through Phase III clinical trials, observational studies, evidence synthesis, and clinical guidelines development.
完成時間為 3 小時
9 個視頻 （總計 73 分鐘）, 6 個閱讀材料, 1 個測驗
9 個視頻
T2 - Translation to Patients - Part I (7:34)7分鐘
T2 - Translation to Patients - Part II (6:50)6分鐘
T2 - Translation to Patients - Part III (6:50)6分鐘
T2 - Translation to Patients - Part IV (9:55)9分鐘
T3 - Translation to Practice - Introduction (8:36)8分鐘
T3 - Translation to Practice - Part 1 (6:18)6分鐘
T3 - Translation to Practice - Part II (8:22)8分鐘
T3 - Translation to Practice - Part III (9:26)9分鐘
6 個閱讀材料
Using Electronically Available Inpatient Hospital Data for Research15分鐘
The mPower study, Parkinson disease mobile data collected using ResearchKit15分鐘
Moving from the Laboratory Bench to Patients’ Bedside: Considerations for Effective Therapy with Stem Cells15分鐘
Partnering to Reduce Environmental Hazards Through a Community-Based “Healthy Home Museum”:Education for Action15分鐘
Health Services Research: An Evolving Definition of the Field10分鐘
White Paper on CTSA Consortium Role in Facilitating Comparative Effectiveness Research15分鐘
1 個練習
Module 2 Quiz40分鐘
完成時間為 4 小時
T4 - Translation to Communities and Participating in Clinical and Translational Research
The fifth lesson of Introduction to Translational Science provides an introduction to T4 research, which is research that translates findings from practices (T3 research) to communities, both domestic and globally. T4 research is often conducted through prevention and outcome studies, mass screening studies, and health policy studies.The sixth lesson of Introduction to Translational Science provides an overview of how interested individuals can participate in clinical and translational research; as an independent research, as a clinical research professional, and as a study volunteer. The final segment of the module demonstrates what a typical study volunteer will encounter if they are selected to participate in a clinical trial.
完成時間為 4 小時
10 個視頻 （總計 74 分鐘）, 8 個閱讀材料, 1 個測驗
10 個視頻
T4 - Translation to Communities - Part I (9:15)9分鐘
T4 - Translation to Communities - Part II (10:09)10分鐘
T4 - Translation to Communities - Part III (7:43)7分鐘
T4 - Translation to Communities - Part IV (6:58)6分鐘
T4 - Translation to Communities - Part V (9:04)9分鐘
Participating in Clinical and Translational Science - Introduction (4:12)4分鐘
Participating in Clinical and Translational Science - Part I (5:26)5分鐘
Participating in Clinical and Translational Science - Part II (3:51)3分鐘
Participating in Clinical and Translational Science - Part III (8:13)8分鐘
8 個閱讀材料
Clinical and Translational Science: From Bench-Bedside to Global Village10分鐘
Engaging the Community in the Dissemination, Implementation, and Improvement of Health-Related Research10分鐘
Theoretical Model of Critical issues in Informed Consent in HIV Vaccine Trials15分鐘
Chronic Diseases: The Emerging Pandemic5分鐘
Recommendations for Planning Pilot Studies in Clinical and Translational Research10分鐘
Strengthening the Career Development of Clinical Translational Scientist Trainees: A Consensus Statement of the Clinical Translational Science Award (CTSA) Research Education and Career Development Committees10分鐘
Defining Translational Research: Implications for Training15分鐘
Assessing Research Participants’ Perceptions of their Clinical Research Experiences15分鐘
1 個練習
Module 3 Quiz40分鐘
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