課程信息
4.8
481 個評分
109 個審閱
100% 在線

100% 在線

立即開始,按照自己的計劃學習。
可靈活調整截止日期

可靈活調整截止日期

根據您的日程表重置截止日期。
初級

初級

完成時間(小時)

完成時間大約為8 小時

建議:3 weeks, 1.5 hours per week...
可選語言

英語(English)

字幕:英語(English)...

您將獲得的技能

CancerMolecular BiologyCancer BiologyCancer Stem Cells
100% 在線

100% 在線

立即開始,按照自己的計劃學習。
可靈活調整截止日期

可靈活調整截止日期

根據您的日程表重置截止日期。
初級

初級

完成時間(小時)

完成時間大約為8 小時

建議:3 weeks, 1.5 hours per week...
可選語言

英語(English)

字幕:英語(English)...

教學大綱 - 您將從這門課程中學到什麼

1
完成時間(小時)
完成時間為 1 小時

History and Overview of Metastasis

In this first module, we'll concentrate on the history and overview of metastasis and give you a flavor of how cancer is defined as well as some of the history surrounding how we began to understand metastasis. ...
Reading
5 個視頻(共 18 分鐘), 1 個測驗
Video5 個視頻
Introduction to History and Overview of Metastasis分鐘
History and Overview of Metastasis4分鐘
History of Metastasis Theory4分鐘
Introduction to the Sequential Steps of Metastasis5分鐘
Quiz1 個練習
History and Overview of Metastasis20分鐘
完成時間(小時)
完成時間為 1 小時

Primary Tumor Growth and Neoangiogenesis

In this module, we'll focus on uncontrolled cell division, which is a defining property of cancer, as well as mutation and neoangiogenesis and their roles in tumor formation. We'll also take a look at a primary tumor microenvironment and its component cell types. ...
Reading
5 個視頻(共 36 分鐘), 1 個測驗
Video5 個視頻
Tumor formation: Uncontrolled cell division12分鐘
The role of mutations in primary tumor formation and evolution11分鐘
Neoangiogenesis: new blood vessel formation in cancer5分鐘
The primary tumor microenvironment: what else affects primary tumor growth?6分鐘
Quiz1 個練習
Primary Tumor Growth and Neoangiogenesis24分鐘
2
完成時間(小時)
完成時間為 1 小時

EMT / Invasion / Intravasation

During this module, we'll turn our attention to the next steps after the initial primary tumor formation, epithelial to mesenchymal transition of cancer cells, and local tumor invasion and intravasation into blood or lymph vessels....
Reading
4 個視頻(共 18 分鐘), 1 個測驗
Video4 個視頻
Epithelial-mesenchymal transition, invasion, and intravision9分鐘
Local Tumor Invasion4分鐘
Intravasation2分鐘
Quiz1 個練習
Invasion and Intravasation14分鐘
完成時間(小時)
完成時間為 1 小時

Survival in the Circulation and Extravasation

We'll now take a close look at cancer survival within the circulation, the role of the circulatory system in metastasis, the genetic determinants of metastatic potential, signalling mechanisms, chemokines, the dock and lock hypothesis, and extravasation. ...
Reading
6 個視頻(共 31 分鐘), 1 個測驗
Video6 個視頻
Glossary of Terms2分鐘
The Circulation4分鐘
How cancer cells survive while in circulation4分鐘
Becoming a circulating tumor cell (CTC) and evading immune detection10分鐘
Homing to a new site in the body and extravasation8分鐘
Quiz1 個練習
Survival in the Circulation and Extravasation24分鐘
3
完成時間(小時)
完成時間為 1 小時

Dormancy and Secondary Tumor Growth

In this module, we'll focus on dormancy and secondary tumor growth and how they contribute to the lethality of cancer. ...
Reading
6 個視頻(共 31 分鐘), 1 個測驗
Video6 個視頻
Metastatic homing5分鐘
Evidence for cancer dormancy4分鐘
Cancer dormancy defined8分鐘
Properties of dormant cancer cells6分鐘
Secondary outgrowth4分鐘
Quiz1 個練習
Dormancy and Secondary Tumor Growth20分鐘
完成時間(小時)
完成時間為 1 小時

Morbidity and Mortality Associated with Metastasis

In the previous modules, we've looked closely at the sequential steps of metastasis and some of the biology of how metastasis occurs. Now, we'll turn our attention to morbidity and mortality, or in other words, how cancer hurts and kills people....
Reading
4 個視頻(共 27 分鐘), 1 個測驗
Video4 個視頻
Distribution of Metastasis: Where do cancers spread?10分鐘
Cancer Syndromes14分鐘
Congratulations1分鐘
Quiz1 個練習
Morbidity and Mortality Associated with Metastasis20分鐘

講師

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Kenneth J. Pienta, M.D.

The Donald S. Coffey Professor of Urology
The James Buchanan Brady Urological Institute
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Jelani Zarif

Prostate Cancer Researcher
The James Buchanan Brady Urological Institute
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Sarah Amend

Prostate Cancer Researcher
The James Buchanan Brady Urological Institute
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Haley Axelrod

Prostate Cancer Researcher
The James Buchanan Brady Urological Institute
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Kenneth Valkenburg

Prostate Cancer Researcher
The James Buchanan Brady Urological Institute

關於 Johns Hopkins University

The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world....

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