Over 500,000 people in the United States and over 8 million people worldwide are dying from cancer every year. As people live longer, the incidence of cancer is rising worldwide, and the disease is expected to strike over 20 million people annually by 2030.
提供方
Understanding Cancer Metastasis
约翰霍普金斯大学
課程信息
45,362 次近期查看
學生職業成果
43%
完成這些課程後已開始新的職業生涯
47%
通過此課程獲得實實在在的工作福利
25%
加薪或升職
您將獲得的技能
CancerMolecular BiologyCancer BiologyCancer Stem Cells
學生職業成果
43%
完成這些課程後已開始新的職業生涯
47%
通過此課程獲得實實在在的工作福利
25%
加薪或升職
100% 在線
立即開始，按照自己的計劃學習。
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初級
完成時間大約為7 小時
建議：3 weeks, 1.5 hours per week
英語（English）
字幕：英語（English）, 阿拉伯語（Arabic）
提供方
约翰霍普金斯大学
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
教學大綱 - 您將從這門課程中學到什麼
完成時間為 1 小時
History and Overview of Metastasis
In this first module, we'll concentrate on the history and overview of metastasis and give you a flavor of how cancer is defined as well as some of the history surrounding how we began to understand metastasis.
完成時間為 1 小時
5 個視頻 （總計 18 分鐘）
5 個視頻
Introduction to History and Overview of Metastasis48
History and Overview of Metastasis4分鐘
History of Metastasis Theory4分鐘
Introduction to the Sequential Steps of Metastasis5分鐘
1 個練習
History and Overview of Metastasis20分鐘
完成時間為 1 小時
Primary Tumor Growth and Neoangiogenesis
In this module, we'll focus on uncontrolled cell division, which is a defining property of cancer, as well as mutation and neoangiogenesis and their roles in tumor formation. We'll also take a look at a primary tumor microenvironment and its component cell types.
完成時間為 1 小時
5 個視頻 （總計 36 分鐘）
5 個視頻
Tumor formation: Uncontrolled cell division12分鐘
The role of mutations in primary tumor formation and evolution11分鐘
Neoangiogenesis: new blood vessel formation in cancer5分鐘
The primary tumor microenvironment: what else affects primary tumor growth?6分鐘
1 個練習
Primary Tumor Growth and Neoangiogenesis24分鐘
完成時間為 1 小時
EMT / Invasion / Intravasation
During this module, we'll turn our attention to the next steps after the initial primary tumor formation, epithelial to mesenchymal transition of cancer cells, and local tumor invasion and intravasation into blood or lymph vessels.
完成時間為 1 小時
4 個視頻 （總計 18 分鐘）
4 個視頻
Epithelial-mesenchymal transition, invasion, and intravision9分鐘
Local Tumor Invasion4分鐘
Intravasation2分鐘
1 個練習
Invasion and Intravasation14分鐘
完成時間為 1 小時
Survival in the Circulation and Extravasation
We'll now take a close look at cancer survival within the circulation, the role of the circulatory system in metastasis, the genetic determinants of metastatic potential, signalling mechanisms, chemokines, the dock and lock hypothesis, and extravasation.
完成時間為 1 小時
6 個視頻 （總計 31 分鐘）
6 個視頻
Glossary of Terms2分鐘
The Circulation4分鐘
How cancer cells survive while in circulation4分鐘
Becoming a circulating tumor cell (CTC) and evading immune detection10分鐘
Homing to a new site in the body and extravasation8分鐘
1 個練習
Survival in the Circulation and Extravasation24分鐘
完成時間為 1 小時
Dormancy and Secondary Tumor Growth
In this module, we'll focus on dormancy and secondary tumor growth and how they contribute to the lethality of cancer.
完成時間為 1 小時
6 個視頻 （總計 31 分鐘）
6 個視頻
Metastatic homing5分鐘
Evidence for cancer dormancy4分鐘
Cancer dormancy defined8分鐘
Properties of dormant cancer cells6分鐘
Secondary outgrowth4分鐘
1 個練習
Dormancy and Secondary Tumor Growth20分鐘
完成時間為 1 小時
Morbidity and Mortality Associated with Metastasis
In the previous modules, we've looked closely at the sequential steps of metastasis and some of the biology of how metastasis occurs. Now, we'll turn our attention to morbidity and mortality, or in other words, how cancer hurts and kills people.
完成時間為 1 小時
4 個視頻 （總計 27 分鐘）
4 個視頻
Distribution of Metastasis: Where do cancers spread?10分鐘
Cancer Syndromes14分鐘
Congratulations1分鐘
1 個練習
Morbidity and Mortality Associated with Metastasis20分鐘
審閱
4.8
來自UNDERSTANDING CANCER METASTASIS的熱門評論
由 RB 提供Feb 8, 2017
Good course, but why researchers whant to hold/control cancer in a human and not rebuild the destroyed mechanisms of autoregul;ation by genetic engeneering for example? That would be true cure.
由 RW 提供Jun 3, 2018
It is a beautifully designed course. it never gets boring. The best part is that you can learn at your own pace. Thank you all the instructors and Coursera for making the content available.
由 MA 提供Jan 12, 2017
That's was Avery good experience on the course it's really beneficial and very helpful and I want to thank doctors that had taken apart in explaining cancer metastasis thanks very much
由 GG 提供Jul 29, 2017
it was an amazing course! everything was clear and well-explained.. i had fun and learned alot! thank you coursera! this was my first course and i really enjoyed every minute of it!
由 MM 提供Aug 14, 2017
This course is completely informative and easily understandable for the beginners especially. Thanks to Coursera and John Hopkins University for the wonderful course.
由 KK 提供Feb 26, 2018
Short, concise, to the point, and yet slow enough that it was easy to understand, grasp and remember the knowledge that was being taught. Overall very enjoyable :)
由 CS 提供Jun 22, 2019
Week 1 part 2 was particularly incredible in the clarity of explanations. course in general was fantastic, thank you all for making it and sharing your expertise.
由 TH 提供Jan 28, 2018
Very interesting and informative. Well spoken and written. Slides, cartoons, pictures etc were captivating. Hope you will off more cancer courses in the future!
由 HA 提供Jul 6, 2019
It was a well designed course which helped me to understand cancer metastasis and associated risks. This course was very helpful and easy to understand.
由 SA 提供Mar 26, 2020
Thoroughly enjoyed the course. Loved the explanations. Looking forward to more Cancer Biology courses from your University and laboratory. Thank you!
由 SA 提供Jul 25, 2019
unique content and method of teaching\n\nthank you for this course instructors especially Dr.Kenneth\n\n, i hope to get more courses designed by them
由 S 提供Dec 4, 2017
Very good course and liked the way information presented however speech recognition quality could have been better... Please take care.. Thank you
由 AV 提供Nov 18, 2018
This course really helped me gain a better understanding of cancer dissemination / progression, and I'm now even more interested in the field!
由 SW 提供Mar 24, 2018
Excellent, very clear explanation, full and detailed, without ever talking down to a non-clinical, non-scientifically trained student.
由 SS 提供Mar 27, 2020
learning this course was interesting.it was very easy and simple for understanding. Thank you for all the people behind this course
由 AP 提供Jun 4, 2017
Very helpful in understanding basic concepts.! Thank you so much for the effort You put in to make us understand the concepts.!
由 IM 提供Apr 29, 2018
A great course and a must for every beginner in Cancer research. I see the only disadvantage of this course is its short length
由 ZM 提供Jan 31, 2019
It's just amazing. Though i have postgraduate degree in Cancer but courses like these makes you think to what you are missing.
由 M 提供Jan 24, 2020
I absolutely loved it. The whole module was perfectly prepared and mentors excellently portrayed the whole thing. Thank you.
由 AS 提供Jun 1, 2019
easy understanding ,quick learning ,more information is been gathered in less time ,,thank you entire team of johnhopkins
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