Over 500,000 people in the United States and over 8 million people worldwide are dying from cancer every year. As people live longer, the incidence of cancer is rising worldwide, and the disease is expected to strike over 20 million people annually by 2030.
Understanding Cancer Metastasis
约翰霍普金斯大学課程信息
95,749 次近期查看
學生職業成果
43%
完成這些課程後已開始新的職業生涯
47%
通過此課程獲得實實在在的工作福利
25%
加薪或升職
可分享的證書
完成後獲得證書
100% 在線
立即開始，按照自己的計劃學習。
可靈活調整截止日期
根據您的日程表重置截止日期。
初級
完成時間大約為5 小時
英語（English）
字幕：英語（English）, 阿拉伯語（Arabic）
您將獲得的技能
CancerMolecular BiologyCancer BiologyCancer Stem Cells
學生職業成果
43%
完成這些課程後已開始新的職業生涯
47%
通過此課程獲得實實在在的工作福利
25%
加薪或升職
可分享的證書
完成後獲得證書
100% 在線
立即開始，按照自己的計劃學習。
可靈活調整截止日期
根據您的日程表重置截止日期。
初級
完成時間大約為5 小時
英語（English）
字幕：英語（English）, 阿拉伯語（Arabic）
提供方
约翰霍普金斯大学
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
教學大綱 - 您將從這門課程中學到什麼
完成時間為 1 小時
History and Overview of Metastasis
In this first module, we'll concentrate on the history and overview of metastasis and give you a flavor of how cancer is defined as well as some of the history surrounding how we began to understand metastasis.
完成時間為 1 小時
5 個視頻 （總計 18 分鐘）
5 個視頻
Introduction to History and Overview of Metastasis48
History and Overview of Metastasis4分鐘
History of Metastasis Theory4分鐘
Introduction to the Sequential Steps of Metastasis5分鐘
1 個練習
History and Overview of Metastasis20分鐘
完成時間為 1 小時
Primary Tumor Growth and Neoangiogenesis
In this module, we'll focus on uncontrolled cell division, which is a defining property of cancer, as well as mutation and neoangiogenesis and their roles in tumor formation. We'll also take a look at a primary tumor microenvironment and its component cell types.
完成時間為 1 小時
5 個視頻 （總計 36 分鐘）
5 個視頻
Tumor formation: Uncontrolled cell division12分鐘
The role of mutations in primary tumor formation and evolution11分鐘
Neoangiogenesis: new blood vessel formation in cancer5分鐘
The primary tumor microenvironment: what else affects primary tumor growth?6分鐘
1 個練習
Primary Tumor Growth and Neoangiogenesis24分鐘
完成時間為 1 小時
EMT / Invasion / Intravasation
During this module, we'll turn our attention to the next steps after the initial primary tumor formation, epithelial to mesenchymal transition of cancer cells, and local tumor invasion and intravasation into blood or lymph vessels.
完成時間為 1 小時
4 個視頻 （總計 18 分鐘）
4 個視頻
Epithelial-mesenchymal transition, invasion, and intravision9分鐘
Local Tumor Invasion4分鐘
Intravasation2分鐘
1 個練習
Invasion and Intravasation14分鐘
完成時間為 1 小時
Survival in the Circulation and Extravasation
We'll now take a close look at cancer survival within the circulation, the role of the circulatory system in metastasis, the genetic determinants of metastatic potential, signalling mechanisms, chemokines, the dock and lock hypothesis, and extravasation.
完成時間為 1 小時
6 個視頻 （總計 31 分鐘）
6 個視頻
Glossary of Terms2分鐘
The Circulation4分鐘
How cancer cells survive while in circulation4分鐘
Becoming a circulating tumor cell (CTC) and evading immune detection10分鐘
Homing to a new site in the body and extravasation8分鐘
1 個練習
Survival in the Circulation and Extravasation24分鐘
完成時間為 1 小時
Dormancy and Secondary Tumor Growth
In this module, we'll focus on dormancy and secondary tumor growth and how they contribute to the lethality of cancer.
完成時間為 1 小時
6 個視頻 （總計 31 分鐘）
6 個視頻
Metastatic homing5分鐘
Evidence for cancer dormancy4分鐘
Cancer dormancy defined8分鐘
Properties of dormant cancer cells6分鐘
Secondary outgrowth4分鐘
1 個練習
Dormancy and Secondary Tumor Growth20分鐘
完成時間為 1 小時
Morbidity and Mortality Associated with Metastasis
In the previous modules, we've looked closely at the sequential steps of metastasis and some of the biology of how metastasis occurs. Now, we'll turn our attention to morbidity and mortality, or in other words, how cancer hurts and kills people.
完成時間為 1 小時
4 個視頻 （總計 27 分鐘）
4 個視頻
Distribution of Metastasis: Where do cancers spread?10分鐘
Cancer Syndromes14分鐘
Congratulations1分鐘
1 個練習
Morbidity and Mortality Associated with Metastasis20分鐘
審閱
來自UNDERSTANDING CANCER METASTASIS的熱門評論
由 MS 提供2020年7月1日
A big thanks to John Hopkins University for this course the faculty of this university is one of the best faculty i have ever seen all things are much clear and confidential. Once again Thanks.
由 RB 提供2017年2月8日
Good course, but why researchers whant to hold/control cancer in a human and not rebuild the destroyed mechanisms of autoregul;ation by genetic engeneering for example? That would be true cure.
由 RW 提供2018年6月3日
It is a beautifully designed course. it never gets boring. The best part is that you can learn at your own pace. Thank you all the instructors and Coursera for making the content available.
由 MA 提供2017年1月12日
That's was Avery good experience on the course it's really beneficial and very helpful and I want to thank doctors that had taken apart in explaining cancer metastasis thanks very much
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