How do we infer which genes orchestrate various processes in the cell? How did humans migrate out of Africa and spread around the world? In this class, we will see that these two seemingly different questions can be addressed using similar algorithmic and machine learning techniques arising from the general problem of dividing data points into distinct clusters.
提供方
生物信息学 專項課程加州大学圣地亚哥分校課程信息
8,184 次近期查看
學生職業成果
33%
通過此課程獲得實實在在的工作福利
可分享的證書
完成後獲得證書
100% 在線
立即開始，按照自己的計劃學習。
第 5 門課程（共 7 門）
可靈活調整截止日期
根據您的日程表重置截止日期。
初級
完成時間大約為9 小時
英語（English）
字幕：英語（English）
學生職業成果
33%
通過此課程獲得實實在在的工作福利
可分享的證書
完成後獲得證書
100% 在線
立即開始，按照自己的計劃學習。
第 5 門課程（共 7 門）
可靈活調整截止日期
根據您的日程表重置截止日期。
初級
完成時間大約為9 小時
英語（English）
字幕：英語（English）
提供方
加州大学圣地亚哥分校
UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 10 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom—life is their laboratory.
教學大綱 - 您將從這門課程中學到什麼
完成時間為 5 小時
Week 1: Introduction to Clustering Algorithms
<p>Welcome to class!</p><p>At the beginning of the class, we will see how algorithms for <strong>clustering </strong>a set of data points will help us determine how yeast became such good wine-makers. At the bottom of this email is the Bioinformatics Cartoon for this chapter, courtesy of <a href="http://bearandfox.com" target="_blank" title="Link: http://bearandfox.com">Randall Christopher</a> and serving as a chapter header in the Specialization's bestselling <a href="http://bioinformaticsalgorithms.com" target="_blank">print companion</a>. How did the monkey lose a wine-drinking contest to a tiny mammal? Why have Pavel and Phillip become cavemen? And will flipping a coin help them escape their eternal boredom until they can return to the present? Start learning to find out!</p><p><img width="550" alt="" src="http://bioinformaticsalgorithms.com/images/cover/clustering_cropped.jpg" title="Image: http://bioinformaticsalgorithms.com/images/cover/clustering_cropped.jpg"></p>
完成時間為 5 小時
5 個視頻 （總計 33 分鐘）, 2 個閱讀材料, 3 個測驗
5 個視頻
Which Yeast Genes are Responsible for Wine Making? 6分鐘
Gene Expression Matrices 6分鐘
Clustering as an Optimization Problem 10分鐘
The Lloyd Algorithm for k-Means Clustering 5分鐘
2 個閱讀材料
Course Details10分鐘
Week 1 FAQs (Optional)
1 個練習
Week 1 Quiz20分鐘
完成時間為 4 小時
Week 2: Advanced Clustering Techniques
<p>Welcome to week 2 of class!</p>
完成時間為 4 小時
5 個視頻 （總計 35 分鐘）, 1 個閱讀材料, 3 個測驗
5 個視頻
From Coin Flipping to k-Means Clustering 4分鐘
Expectation Maximization 7分鐘
Soft k-Means Clustering 3分鐘
Hierarchical Clustering 7分鐘
1 個閱讀材料
Week 2 FAQs (Optional)
1 個練習
Week 2 Quiz15分鐘
完成時間為 1 小時
Week 3: Introductory Algorithms in Population Genetics
完成時間為 1 小時
2 個閱讀材料
2 個閱讀材料
Statement on This Week's Material10分鐘
How Have Humans Populated the Earth?10分鐘
1 個練習
Week 3 Quiz10分鐘
關於 生物信息学 專項課程
Join Us in a Top 50 MOOC of All Time!
How do we sequence and compare genomes? How do we identify the genetic basis for disease? How do we construct an evolutionary Tree of Life for all species on Earth?
When you complete this Specialization, you will learn how to answer many questions in modern biology that have become inseparable from the computational approaches used to solve them. You will also obtain a toolkit of existing software resources built on these computational approaches and that are used by thousands of biologists every day in one of the fastest growing fields in science.
Although this Specialization centers on computational topics, you do not need to know how to program in order to complete it. If you are interested in programming, we feature an "Honors Track" (called "hacker track" in previous runs of the course). The Honors Track allows you to implement the bioinformatics algorithms that you will encounter along the way in dozens of automatically graded coding challenges. By completing the Honors Track, you will be a bioinformatics software professional!
Learn more about the Bioinformatics Specialization (including why we are wearing these crazy outfits) by watching our introductory video.
You can purchase the Specialization's print companion, Bioinformatics Algorithms: An Active Learning Approach, from the textbook website.
Our first course, "Finding Hidden Messages in DNA", was named a top-50 MOOC of all time by Class Central!
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