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返回到 临床试验的设计和解释

學生對 约翰霍普金斯大学 提供的 临床试验的设计和解释 的評價和反饋

4.7
3,650 個評分
623 條評論

課程概述

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

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TS
2018年7月3日

High quality course ! covering important areas and detailed lectures, more and better than a mere introduction. Congrats ! My only regret : I'd have liked to hear more about NI and equivalence trials

CC
2020年6月4日

I would highly recommend this course as I found it well-structured and helpful. After studying all the materials, I gained a great amount of knowledge in designing and interpretating clinical trail.

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1 - 临床试验的设计和解释 的 25 個評論(共 618 個)

創建者 João P J P

2018年11月18日

I think that the course should provide a written material in order to deepen the learning process.

創建者 valentina c

2017年8月25日

Useful to get a general understanding of the complexity of a clinical trials and the many aspects that need to be taken into account. it would be incredibly helpful to have a more advanced and statistically-oriented module following this one.

創建者 Oli S

2019年9月19日

This course would be most useful to the participant if pursued within a short time-frame, of maximum of 6 weeks. Both lecturers were clear and good communicators. I would take more of their classes.

創建者 Diana E V G

2017年5月29日

One of the best online courses I have taken so far at Coursera. Very helpful if you are new to the field and helps you to understand and interpret clinical data. I highly recommend this course.

創建者 Mary C V

2018年12月3日

A great course for people working in the Clinical Research industry! I definitely recommend!

創建者 Louise E

2020年7月26日

The course was well designed and I enjoyed learning again.

I did wish that my course certificate gave my overall grade for the course, which was 100% in all modules. I wouldn't have kept retaking certain parts if I'd know the grade didn't appear on the certificate. Also, for non-US English speakers, the narration can be quite fast, which can make it a bit hard to follow at times. In addition, for some of the discussion posts, it would be better to use articles from publications that we don't have to subscribe to and also to assume the learner has no experience in the field, if possible.

創建者 Olga M

2019年7月1日

Great course for basic introduction to clinical trials design, features and guidelines.

創建者 Kevin S

2019年6月16日

It is hard to describe what I didn't like about this course. I have a reasonable statistical background as well as a basic science and public health background, so I may be overly familiar with the material. I didn't find that going through the material helped me beyond what I could intuit from the basic principles of how to do a study. This isn't good, because I feel like someone without my background would be overwhelmed by the information presented and not be able to follow it. I also believe the lecture style was too conversational and not very organized. It feels like a little bit too much like the introduction to a journal club with 3rd year graduate students. The course should be for novices. Ultimately, everything felt like it was being described rather than taught. One positive I can say, is that I think the basic contents of the course are good, they just need to be organized properly and distilled down and focused. Instructors should resist any urge to randomly jump into discussions which are above the intended level of the course.

創建者 PUNEET M

2020年4月4日

Indeed a great course, simple, informative, and exactly what is expected to a person associated with clinical research. Its more apt for a new investigator or writer to understand the basics.. a little more than the basics. :)

創建者 Thomas P S

2018年7月4日

High quality course ! covering important areas and detailed lectures, more and better than a mere introduction. Congrats ! My only regret : I'd have liked to hear more about NI and equivalence trials

創建者 cen c

2020年6月5日

I would highly recommend this course as I found it well-structured and helpful. After studying all the materials, I gained a great amount of knowledge in designing and interpretating clinical trail.

創建者 Jose Q

2019年10月26日

Excellent beginner course on design and interpretation of clinical trials, complements a lot of what I reviewed on my classes and I would like to take a more advanced course on the topic. Thank you.

創建者 Alba M M L

2019年1月30日

This is a really good course if you are starting your journey in a clinical trials. It's really helpful to learn vocabulary related to this field.

創建者 SARA E C C

2019年1月5日

This is a very well structured course and great to have a basic and general idea of the main points to verify when either designing or, most importatnt in my case, how to evaluate publications about clinical trials. I would recommend this course for users with at least a minimum scientific background. The videos are engaging, and the reading material supplied (mostly for ethics and reporting) are complete and helps to give depth to what I learned. Congratulations to the organizers. I will definitely take more courses from this University, online, in the future.

創建者 Lorenzo G

2020年4月13日

I took this course right after I started working in Phase 1 and 2 clinical trials. This is a very insightful course that includes many aspects of clinical research, which are very important to know regardless if your role in the clinic. The lectures are well structured and are just the right length. I completed it in a weekend and got my certificate right away, definitely recommended for anyone who wishes to be part of this industry.

創建者 Latoya G

2020年4月15日

I commend and thank Dr Holbrook and Dr Drye for creating such a comprehensive course in such a short time frame. I am pleased with level of knowledge i gained. I will definitely be completing other related courses from Johns Hopkins University.

創建者 Daniel M F

2020年12月17日

Very good balance of general and in-depth content as well as technical and non-technical information. Well structured so it is easy to follow. Both presenters have an adequate pace and clear voice.

創建者 Ayeesha M

2016年3月20日

This course is well-designed, well-paced and well-structured. The study examples described in this course really help you understand the importance of design and interpretation of clinical trials.

創建者 Tsinatkeab T

2018年5月31日

I was able to learn a lot from this course. The lectures and the sequence of the presentations were logical and clear to understand. I will definitely recommend this course for my colleagues.

創建者 Lisa L

2019年4月5日

Thrilled to finish this course. I'm gonna use what I learnt from this course in my current job and share with my colleagues.

創建者 Nancy H

2019年3月20日

Really great course that goes over clinical trials and very important terms in order to understand the topic well.

創建者 Deleted A

2019年5月5日

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創建者 VICTOR P G

2016年4月7日

This course has really helped me in my understanding and appreciation of how research should be conducted.

Thank You

創建者 Martin W

2020年4月17日

Solid Introduction. Listen to the videos (almost no graphics used, mostly notes), read the recommended texts and answer the questions. That was my experience. Classic teacher-centred teaching, besides the questionnaire no real active part. I asked one topic related question in the forum, no answer. If you keep all of that in mind, still recommended.

創建者 katayoun k

2016年6月29日

the lessons were too long in duration and i was really bored because the teaching didn't have anything engaging me to be more eager to listen and all the slides were with the same background and design and there were no pictures or animation or fun stuff to create some kind of diversity in the progress of the course.