課程信息
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101 個評分
27 個審閱
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完成時間(小時)

完成時間大約為19 小時

建議:1-2 hours/week...
可選語言

英語(English)

字幕:英語(English)...
100% online

100% online

立即開始,按照自己的計劃學習。
可靈活調整截止日期

可靈活調整截止日期

根據您的日程表重置截止日期。
完成時間(小時)

完成時間大約為19 小時

建議:1-2 hours/week...
可選語言

英語(English)

字幕:英語(English)...

教學大綱 - 您將從這門課程中學到什麼

1
完成時間(小時)
完成時間為 2 小時

Introduction and History of Bioinformatics

Welcome to “Bioinformatics: Introduction and Methods! Upon completion of this module you will be able to: become familiar with the essential concepts of bioinformatics; explore the history of this young area; experience how rapidly bioinformatics is growing. Our supplementary materials will give you a better understanding of the course lectures through they are not required in quizzes or exams...
Reading
4 個視頻(共 69 分鐘), 2 個閱讀材料, 1 個測驗
Video4 個視頻
History of Bioinformatics30分鐘
Bioinformatics in Mainland China8分鐘
About This Course9分鐘
Reading2 個閱讀材料
Readings10分鐘
Slides10分鐘
Quiz1 個練習
Introduction and History of Bioinformatics20分鐘
2
完成時間(小時)
完成時間為 2 小時

Sequence Alignment

Upon completion of this module, you will be able to: describe dynamic programming based sequence alignment algorithms; differentiate between the Needleman-Wunsch algorithm for global alignment and the Smith-Waterman algorithm for local alignment; examine the principles behind gap penalty and time complexity calculation which is crucial for you to apply current bioinformatic tools in your research; experience the discovery of Smith-Waterman algorithm with Dr. Michael Waterman himself....
Reading
7 個視頻(共 99 分鐘), 2 個閱讀材料, 1 個測驗
Video7 個視頻
Global Alignment by Dynamic Programming14分鐘
From Global to Local6分鐘
Alignment with Affine Gap Penalty and Calculation of Time Complexity of The Needleman-Wunsch Algorithm6分鐘
Interview with M. S. Waterman Waterman29分鐘
Supplement on Homology & Similarity, Similarity Matrix and Dot Matrix (English Subtitles)10分鐘
Student Presentation (English Subtitles)18分鐘
Reading2 個閱讀材料
Readings10分鐘
Slides10分鐘
Quiz1 個練習
Sequence Alignment18分鐘
3
完成時間(小時)
完成時間為 1 小時

Sequence Database Search

Upon completion of this module, you will be able to: become familiar with sequence databse search and most common databases; explore the algoritm behind BLAST and the evaluation of BLAST results; ajdust BLAST parameters base on your own research project....
Reading
3 個視頻(共 41 分鐘), 2 個閱讀材料, 1 個測驗
Video3 個視頻
BLAST Algorithm: A Primer13分鐘
Student Presentation (English Subtitles)15分鐘
Reading2 個閱讀材料
Readings10分鐘
Slides10分鐘
Quiz1 個練習
Sequence Database Search10分鐘
4
完成時間(小時)
完成時間為 1 小時

Markov Model

Upon completion of this module, you will be able to: recognize state transitions, Markov chain and Markov models; create a hidden Markov model by yourself; make predictuions in a real biological problem with hidden Markov model....
Reading
4 個視頻(共 47 分鐘), 2 個閱讀材料, 1 個測驗
Video4 個視頻
Hidden Markov Model11分鐘
Predict with Hidden Markov Model10分鐘
Student Presentation16分鐘
Reading2 個閱讀材料
Readings10分鐘
Slides10分鐘
Quiz1 個練習
Markov Model 14分鐘

講師

Avatar

Ge Gao 高歌, Ph.D.

Assistant Professor, Principle Investigator
Center for Bioinformatics, School of Life Science
Avatar

Liping Wei 魏丽萍, Ph.D.

Professor, Director
Center for Bioinformatics, School of Life Sciences

關於 Peking University

Peking University is determined to make its education openly accessible to students in China and around the world. With over 3000 faculty members, Peking University offers excellence in teaching and learning. Founded in 1898, Peking University (PKU) was the first national comprehensive university in China. For the past 115 years, with its hundreds of thousands of outstanding alumni, Peking University has made prominent contributions in the humanities and sciences to further China's prosperity and progress....

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