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學生對 加州大学圣地亚哥分校 提供的 Genome Assembly Programming Challenge 的評價和反饋

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303 個評分
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56 條評論

課程概述

In Spring 2011, thousands of people in Germany were hospitalized with a deadly disease that started as food poisoning with bloody diarrhea and often led to kidney failure. It was the beginning of the deadliest outbreak in recent history, caused by a mysterious bacterial strain that we will refer to as E. coli X. Soon, German officials linked the outbreak to a restaurant in Lübeck, where nearly 20% of the patrons had developed bloody diarrhea in a single week. At this point, biologists knew that they were facing a previously unknown pathogen and that traditional methods would not suffice – computational biologists would be needed to assemble and analyze the genome of the newly emerged pathogen. To investigate the evolutionary origin and pathogenic potential of the outbreak strain, researchers started a crowdsourced research program. They released bacterial DNA sequencing data from one of a patient, which elicited a burst of analyses carried out by computational biologists on four continents. They even used GitHub for the project: https://github.com/ehec-outbreak-crowdsourced/BGI-data-analysis/wiki The 2011 German outbreak represented an early example of epidemiologists collaborating with computational biologists to stop an outbreak. In this online course you will follow in the footsteps of the bioinformaticians investigating the outbreak by developing a program to assemble the genome of the E. coli X from millions of overlapping substrings of the E.coli X genome....

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SH

2020年10月20日

Really enjoyable and also challenging specialization. I also enjoyed this capstone too. I gathered my interest in Algorithms and Bioinformatics field.

AS

2018年8月4日

I would like to say thank you to all who have created this course and specialization! Good material, excellent lecturers!

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51 - Genome Assembly Programming Challenge 的 57 個評論（共 57 個）

創建者 Xi Y

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2017年2月16日

challenging

創建者 Dave

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2020年7月11日

very good!

創建者 VontMan

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2019年8月28日

The topic is very interesting but it is very rushed and it is very challenging to pass the test

創建者 Cheung W C

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2021年6月29日

Too hard.

創建者 Weidong X

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2016年11月26日

good.

創建者 Dmitri M

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2017年5月9日

I wish I had the choice of pursuing graph algorithms, when I signed up for the specialization with the promise of selecting one of the two Capstone projects. Bioinformatics? I wanted the other one on practical graph algorithm applications. There are already two dedicated courses by Pevzner and et al, which would have prepared us better for this too specialized and impractical Capstone project...

創建者 Bohdan S

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2021年2月21日

Couldn't find any good explanation why THIS is included as the specialization's last course. It just makes no sense.

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