課程信息
4.6
521 ratings
127 reviews
The course will cover the topics related to antimicrobial resistance with basic definitions and overview on antimicrobials their use and the emergence and spread of resistance. The course will guide you through the concepts and the importance of resistance spread and dissemination and how that happens. It will show you how bacteria become resistant and which mechanisms they might use for this. And as part of the course you will also receive some training in methods for antimicrobial susceptibility testing (AST) and detection of specific resistance in the microbiological laboratories with the basic methods available and with focus on the obtention of good quality results which can be interpreted and used for different purposes. Additionally, it will show you how to use genomic analysis tools to analyze whole genome sequencing data to detect resistance genes (and or other genes of interest) in a simple and easy way using online tools freely available. In the new new version an additional module including detection of specific resistance mechanisms was added. After this course you should be able to: 1. Describe the most important families of antimicrobials and mode of action 2. Understand the basic concepts of antimicrobial resistance from several perspectives (clinical, research and microbiological) 3. Enumerate and describe how bacteria can become resistant and the mechanisms that may be involved in that process 4. Describe how antimicrobial resistance emerges and spreads around the world including concepts of antimicrobial resistance transfer, selection and dissemination 5. Enumerate the methods used for antimicrobial susceptibility testing (AST) 6. Compare dilution and diffusion methods and know the basic techniques of agar disk diffusion, broth dilution and agar dilution methods 7. Have detailed theoretical knowledge on how to perform the main methods in a laboratory 8. Know the basic concepts about analysis and interpretation of results of AST, including different breakpoints, cut-off setting and their applications. 9. Understand the importance and related concepts related to quality management and quality assurance method standardization, applied to AST 10. Relate the information obtained in this course with real cases of resistant bacteria spreading in patients, the community, animals or the environment 11. Relate the phenotypical results with results from genotyping using molecular techniques for detection of resistance mechanisms 12. Understand the concept and be able to apply genomic analysis tools used to detect resistance genes and other relevant genes from Whole Genome Sequencing (WGS) data (with demonstration of selected online tools) Disclaimer: Please note that the guidelines and methods referred or links included in these materials are updated when the videos lectures are produced and before the course is released, however these might become outdated with time....
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100% 在線課程

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Intermediate Level

中級

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建議:5 weeks of study, 1-2 hours/week

完成時間大約為7 小時
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English

字幕:English

您將獲得的技能

Drug ResistanceAntimicrobialGenomeMicrobiology
Globe

100% 在線課程

立即開始,按照自己的計劃學習。
Calendar

可靈活調整截止日期

根據您的日程表重置截止日期。
Intermediate Level

中級

Clock

建議:5 weeks of study, 1-2 hours/week

完成時間大約為7 小時
Comment Dots

English

字幕:English

教學大綱 - 您將從這門課程中學到什麼

1

章節
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完成時間為 20 分鐘

Welcome to the course

This module is basically a welcome to the course were you can find information on the Course structure, the contents you will be learning in the next modules, the grading, and introduction to the instructors and to the teaching material....
Reading
1 個視頻(共 10 分鐘), 1 個閱讀材料
Video1 個視頻
Reading1 個閱讀材料
NOTE: This version has been added an additional module on detection of Specific resistances10分鐘
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完成時間為 1 小時

Module A- Antimicrobial and antimicrobial action

Antimicrobials and antimicrobial action ( includes two lectures and one quiz). Here you will learn a lot about antibiotics/ antimicrobials and you will know more about:what they are, where do they come from, what are the major groups and how can we classify them, how do they have an effect, how do they act on the bacterial cells...
Reading
2 個視頻(共 41 分鐘), 1 個測驗
Video2 個視頻
Lecture 2- Antimicrobials and antimicrobial action16分鐘
Quiz1 個練習
Quizz Lectures 1-2 (antimicrobials)10分鐘

2

章節
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完成時間為 1 小時

Module B - Antimicrobials and resistance

This module containd information about antimicrobials and the development of resistance in bacteria including causes for resistance and their mechanisms, as well as an insight in how resistance disseminates and how it can be selected....
Reading
4 個視頻(共 54 分鐘), 1 個測驗
Video4 個視頻
Lecture 4- Antimicrobials and resistance- causes and mechanisms14分鐘
Lecture 5- Antimicrobial resistance- emergence and dissemination12分鐘
Lecture 6- Antimicrobials and resistance - selection8分鐘
Quiz1 個練習
Q2- Quizz Lectures 3-6 (antimicrobial resistance)10分鐘

3

章節
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完成時間為 2 小時

Module C- Antimicrobial susceptibility testing

This module deals with antimicrobial susceptibility testing in the laboratory: its importance and use, descriptions of the methods and their applications and detailed descriptions of the procedures applied for the main methods....
Reading
5 個視頻(共 108 分鐘), 1 個測驗
Video5 個視頻
Lecture 8- Antimicrobial susceptibility testing- methods17分鐘
Lecture 9- Antimicrobial susceptibility testing- disk diffusion18分鐘
Lecture 10- Antimicrobial susceptibility testing- agar dilution34分鐘
Lecture 11- Antimicrobial susceptibility testing- broth dilution19分鐘
Quiz1 個練習
Q3- Quizz Lectures 7-11 (AST)12分鐘

4

章節
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完成時間為 1 小時

Module D- Interpretation

This module gives practical insight on how to interpret antimicrobial susceptibility results....
Reading
1 個視頻(共 29 分鐘), 1 個測驗
Quiz1 個練習
Q4- Quizz Lecture 12 (interpretation AST)8分鐘
Clock
完成時間為 1 小時

Module E- Quality assurance

This module is dedicated to Quality management and Quality assurance (QA/ Quality control (QC) procedures and use of QC strains to assure the qulaity of results of antimicrobial susceptibility testing: importance, elements and principles....
Reading
2 個視頻(共 33 分鐘), 1 個測驗
Video2 個視頻
Lecture 14- Quality assurance when doing antimicrobial susceptibility testing22分鐘
Quiz1 個練習
Q5- Quizz Lectures 13-14 (Quality assurance)6分鐘
4.6
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創建者 DJNov 15th 2016

It was really a good lectures and please I want to know about my certificate in have already purchased this course and submitted all\n\nThe documents let me know when will I get my certificate .

創建者 AASep 24th 2017

This i very good course. i recommended to all microbiology and molecular biology students. All three teachers are very good. specially last week lecture about molecular detection of MRSA. CRE.

講師

Lina Cavaco

Ext Researcher
Copenhagen University- ICMM /Statens Serum Institut - Department for Bacteria, Parasites and Fungi

Pimlapas Leekitcharoenphon

PostDoc
Research Group for Genomic Epidemiology, DTU Food

Rene S. Hendriksen

Professor, PhD
Technical University of Denmark, National Food Institute, Research Group of Genomic Epidemiology

關於 Technical University of Denmark (DTU)

DTU focuses on research in technical and natural sciences that contributes to the development of society. As an industrially orientated university, our goal is to supply high-level international research based on combining theory with constructing models and empirical methods....

常見問題

  • Once you enroll for a Certificate, you’ll have access to all videos, quizzes, and programming assignments (if applicable). Peer review assignments can only be submitted and reviewed once your session has begun. If you choose to explore the course without purchasing, you may not be able to access certain assignments.

  • When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.

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